This easy turkey tetrazzini is the best way to use leftover holiday turkey! It’s a creamy, cheesy flavorful pasta casserole dish that comes together with simple ingredients.
If you love an easy casserole dish for dinner, other favorites include baked spaghetti, easy baked ziti and this pizza pasta casserole.
Table of Contents
Easy Turkey Tetrazzini Recipe
This turkey tetrazzini recipe is the best way to use leftover roasted turkey from your Thanksgiving menu! And while I love turkey sandwiches, too, this is one of my favorite leftover turkey recipes!
Just like chicken tetrazzini, this baked pasta dish is easy to make and takes less than 10 ingredients. It’s a comforting family favorite along with healthy turkey chili. Other classic recipes we make post-turkey dinner include homemade turkey pot pie and leftover turkey soup.
Recipe Ingredients
Combine all these ingredients together to make the best turkey tetrazzini casserole ever!
Find the full printable recipe with specific measurements below.
- Noodles: You can use either thin spaghetti or linguine type of noodle.
- Butter: Salted or unsalted butter works well with this recipe.
- Onion & garlic: Finely chop and cook until golden for flavor.
- Turkey breast: Use up your leftover Thanksgiving turkey.
- Cream of mushroom soup: This will add in thickness and flavor to your noodles.
- Sour cream: Thickens up the sauce plus helps with the creaminess in the mixture.
- Cheese: Freshly shredded mozzarella & parmesan cheese will give this dish the cheesiest noodles.
How to Make Turkey Tetrazzini
- Cook pasta. Cook pasta al dente, according to package directions. Then drain the pasta, reserving 1/2 cup pasta water.
- Make the sauce. Melt the butter over medium-heat in a skillet. Add in the chopped onions and cook for 3 to 5 minutes. Then add minced garlic and cook an additional minute. Next add in the turkey, cream of mushroom soup and sour cream. If you need to thin the sauce out a little, add in the pasta water.
- Combine. Toss together the sauce and noodles, then pour mixture in a buttered 8×8″ baking dish.
- Bake in the oven. Top with cheese and bake in oven at 350°F for 25-30 minutes, or until the top is bubbly and lightly golden.
Tips and Substitutions
This tetrazzini casserole dish is perfect for using leftovers and having an extra meal during the week.
- Use homemade cream of mushroom soup if you’d prefer to make your own.
- Add in 1/2 cup sliced mushrooms with the chopped onions.
- You can also use cooked chicken instead of turkey for a chicken tetrazzini.
- For more texture, feel free to sprinkle some bread crumbs on top. We love the crunch from Panko breadcrumbs.
- You can substitute chopped onions and minced garlic with 1/2 teaspoon both onion powder and garlic powder. Simply mix the seasonings with the melted butter.
- Frozen peas also taste yummy in this dish. Mix them in when you stir together the sauce and noodles.
Are you looking for more casserole dishes?! Try this breakfast casserole, meatball casserole, or this Mexican casserole.
More Baked Pasta Dish Recipes
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Turkey Tetrazzini recipe
Video
Equipment
- 8×8 baking dish
Ingredients
- 8 ounces thin spaghetti , or linguine
- 3 Tablespoons butter
- ½ cup finely chopped onion
- 1-2 teaspoons minced garlic
- 2-3 cups cooked turkey breast
- 1 cup cream of mushroom soup , or cream of chicken
- ¾ cup sour cream
- 1/2-1 cup shredded mozzarella cheese
- 1-2 Tablespoon grated parmesan cheese
S&P, to taste
Fresh parsley for serving
Instructions
- Prep. Preheat oven to 350°F. Butter a 8×8" baking dish and set aside. Cook 8 ounces of pasta al dente, according to package directions. Drain, reserving 1/2 cup pasta water.
- Saute onion and garlic. In a skillet, melt 3 Tablespoons butter over medium-heat. Add 1/2 cup chopped onions and cook 3-5 minutes. Then add 2 teaspoons minced garlic and cook an additional minute.
- Assemble casserole. Next add in 2-3 cups chopped turkey, 1 cup cream of mushroom soup and 3/4 cup sour cream. Add in pasta water if need to thin out. Salt and pepper to taste. Toss sauce with noodles and pour into baking dish.
- Bake. Sprinkle with 1 cup mozzarella cheese and 2 Tablespoons Parmesan then bake for 25-30 minutes, or until the top is bubbly and lightly golden. Top with fresh parsley if desired.
Notes
Nutrition
Nutrition provided is an estimate. It will vary based on specific ingredients used.
Did you make this recipe? Don’t forget to give it a star rating below!
Recipe FAQs
Tetrazzini is an American dish that is made with diced meat or seafood. It is known to have been originated in San Francisco. The dish is named after the famous opera singer Luisa Tetrazzini. It usually has a buttery cream sauce with mushrooms and topped with cheese.
We love to serve this pasta dish with a big chopped salad and leftover dinner rolls or French bread. Seriously so yummy!
Store leftovers for up to 3-4 days in an airtight container in the refrigerator. You can also freeze leftovers, cool completely then store in an airtight container for up 3 months. Thaw in the fridge, add additional milk, heavy cream or chicken broth when reheating.
This dish makes a great freezer meal. Sometimes I double the recipe and pop one in the freezer for busy weeknights.
To freeze before baking, mix together the noodles with the sauce, then pour into a buttered baking dish. Let cool completely, then add cheese on top. Cover tightly with foil or lid and place in the freezer. Thaw in fridge overnight, then bake in oven at 350°F according to directions.
Categorized as: Casseroles, Dinner, Freezer-Friendly, Freezer-Friendly, Italian, Meal Prep, Nut-Free, Pasta, Thanksgiving
Jamielyn Nye is the founder and recipe creator at I Heart Naptime. She is the author of the I Heart Naptime Cookbook and shares easy family-friendly recipes and desserts for every occasion.
This was great. I used some leftover chicken from a roasted chicken made the day before. It was wonderful. I plan on making 2 batches again soon (1 to freeze). Thanks for sharing this good keeper.
I’m so glad you enjoyed the recipe!